Stipend for MSc student available in the Department of Microbiology. The deadline for submitting applications is June 27, 2021.
Position in the project: student – MSc
Scientific discipline: microbiology, immunology
Job type: stipend
Number of job offers: 1
Remuneration/stipend amount/month: 1 500 PLN/month (non-taxable)
Position starts on: 1 August 2021
Maximum period of contract/stipend agreement: 12 months
Institution: Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow
Project leader: dr Aleksander Grabiec
Project title: Epigenetics of periodontitis: DNA methylation in disease development and as a potential therapeutic target
Project description:
Project is carried out within the First Team programme of the Foundation for Polish Science. The aim of this project is to analyze pathological changes in DNA methylation in gingival cells from patients with periodontitis, identify the influence of Porphyromonas gingialis on DNA methylation in these cells and characterize its biological consequences. Studies performed within this project will not only improve our understanding of this disease, but can also facilitate identification of new therapeutic targets, constituting a foundation for testing new drug classes in the treatment of periodontal disease in the future.
Project is carried out within the First Team programme of the Foundation for Polish Science. The aim of this project is to analyze pathological changes in DNA methylation in gingival cells from patients with periodontitis, identify the influence of Porphyromonas gingialis on DNA methylation in these cells and characterize its biological consequences. Studies performed within this project will not only improve our understanding of this disease, but can also facilitate identification of new therapeutic targets, constituting a foundation for testing new drug classes in the treatment of periodontal disease in the future.
Key responsibilities include:
- Comparison of DNA methylation profiles, expression of methylation-regulating enzymes, inflammatory and antimicrobial responses between primary gingival fibroblasts derived form healthy donors and periodontitis patients.
- Study of the influence of DNA methyltransferase inhibitors on the viability, inflammatory and antibacterial response of periodontal ligament fibroblasts.
Profile of candidates/requirements:
- BSc degree (or equivalent) in biotechnology, biochemistry or any related field of life sciences obtained before the beginning of the stipend contract (candidates who have not obtained BSc degree before the application deadline must provide a written confirmation of the planned date of BSc completion from their supervisors).
- Strong experience in eukaryotic cell culture and in some of the basic cell biology techniques (qPCR, ELISA and/or Western Blot).
- Experience in anaerobic bacterial cultures would be an advantage.
- Fluency in written and spoken English.
- Good skills in work organization, planning and keeping experimental track record.
- High level of independence, determination and reliability, willingness to work outside of standard office hours.
- Ability to work in a team.
Required documents:
- Application/motivation letter
- CV including description of experience in laboratory work.
- A statement of knowledge and acceptance of the rules on intellectual property and legal protection of intellectual property Forms for points 3 and 5 can be downloaded from http://www.dso.uj.edu.pl/druki-do-pobrania/dokumenty-dla-kandydatow-pracownikow
- Contact information of at least one reference.
- Successful candidate will provide a copy of the BSc diploma before the beginning of the stipend contract.
We offer:
- Participation in competitive and advanced biomedical research and MSc programme at a leading Polish university.
- Work in a well-funded research laboratory using state-of-the-art equipment and techniques.
- Collaboration with leading scientists in the field.
- Possibility to attend international scientific meetings.
Please submit the following documents to: aleksander.grabiec@uj.edu.pl (only candidates considered suitable for the post will be informed by return e-mail).
Application deadline: 27 June 2021
Please include in your offer: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.’’
