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Stipends for MSc student in the Department of Microbiology

Stipends for MSc student in the Department of Microbiology available from 1st July 2019. The closing date for applications is the 15th May 2019.

Position in the project: MSc student 
Scientific discipline: Microbiology, immunology
Job type (employment contract/stipend): stipend
Number of job offers: 2
Remuneration/stipend amount/month: 1 500 PLN/month (non-taxable)
Position starts on: 1.07.2019 and 1.07.2019
Maximum period of contract/stipend agreement: 12 months
Institution: Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow
Project leader: dr Maja Sochalska
Project title: Targeting deregulated expression of anti-apoptotic proteins belonging to the Bcl-2 family in neutrophils as a potential therapy against periodontal disease. In vitro and in vivo analysis. Project is carried out within the First Team programme of the Foundation for Polish Science
 
Project description: The aim of this project is to analyze pathological changes in neutrophils and identify the influence of virulence factors of Porphyromonas gingialis on neutrophil survival and pro-inflammatory functions and characterize its biological consequences in vitro and in vivo. Studies performed within this project will not only improve our understanding of periodontal disease, but can also facilitate identification of new therapeutic targets, constituting a foundation for testing new drug classes in the treatment in the future.
 
Key responsibilities include:
  1. In vitro studies on HoxB8 neutrophils of P. gingivalis virulence factors influence on survival and functions. 
  2. Analysis on Bcl-2-like anti-apoptotic proteins inhibitors on neutrophils survival and functions in vitro. 
  3. Determination of the role of P. gingivalis infection and inflammation in vivo in two mouse models of periodontitis.
  4. Analysis of application of Bcl-2-like inhibitors on development of periodontal disease in vivo.
  5. Ex vivo analysis of neutrophils survival and functions isolated from human blood treated with Bcl-2-like inhibitors.
Profile of candidates/requirements:
  1. BSc degree (or equivalent) in biotechnology, biochemistry or any related field of life sciences stating the expected defense date.
  2. Strong experience in primary eukaryotic cell culture and in basic cell biology techniques (ELISA, Western Blot, flow cytometry) evidenced by results presented in MSc thesis or publication. 
  3. Experience in culturing anaerobic bacteria would be an advantage. 
  4. Experience in leukocyte studies (isolation, culture, stimulations) would be an advantage. 
  5. Experience in analysis of flow cytometric data using GraphPad Prizm and Flow jo Software would be an advantage. 
  6. Fluency in written and spoken English. 
  7. Good skills in work organization, planning and keeping experimental track record. 
  8. High level of independence, determination and reliability, willingness to work outside of standard office hours. 
  9. Ability to work in a team. 
Required documents:
  1. Application/motivation letter 
  2. CV including description of experience in laboratory work
  3. Copy of a BSc degree or a document stating the expected defense date
  4. A statement of knowledge and acceptance of the rules on intellectual property and legal protection of intellectual property Forms for points 3 and 5 can be downloaded from http://www.dso.uj.edu.pl/druki-do-pobrania/dokumenty-dla-kandydatow-pracownikow    
  5. Contact information of at least one reference
We offer:
  • Participation in competitive and advanced biomedical research and PhD programme at a leading Polish university
  • Work in a well-funded research laboratory using state-of-the-art equipment and techniques
  • Collaboration with leading scientists in the field
  • Possibility to attend international scientific meetings

Application deadline: 15.05.2019

Please submit the documents to: maja.sochalska@uj.edu.pl
(only candidates considered suitable for the post will be informed by return e-mail)

Euraxess job/stipend offer (in case of PhD and postdoc positions): https://euraxess.ec.europa.eu/jobs 
 

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